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EMT: the sword of CTC dissemination EMT involves several key changes: reorganization of the epithelial cell cytoskeleton, loss of cell polarity, detachment from the basement membrane, and the acquisition of mesenchymal cell function

But now it's exactly the reverse." Another possible target for modulating microglial activity is the complement system, a signaling pathway that can tag molecular danger signalsor mistakenly, synapsesfor microglia to consume

This method, by delivering medication directly into the bloodstream, bypasses the digestive system, ensuring that the full strength of the medication is available to target the illness swiftly and effectively

doi: 10.1126/science.1227166 55

SPIE , Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XVI