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Its pathogenesis is thought to involve various factors, including insulin resistance, lipotoxicity, gut/nutrient-derived signals, adipocytokines, oxidative stress, and genetic factors

ErgothioneineA diet-derived antioxidant with therapeutic potential

Morning headaches: Increased pressure caused by oxygen level changes often leads to waking with a headache

Mitochondrial function, oxidative stress, inflammation and thrombolytic treatment in ischemic stroke

Overall, adipocytes rich in 6 PUFAs tend to secrete higher TNF-/IL-6 and leptin, whereas 3-rich tissue promotes adiponectin and immune-resolving signals 364,365,366,367
