oxidized glutathione pka Glutathione/Glutaredoxin in Cellular Redox Homeostasis and Signaling GSSG is composed of two reduced GSH molecules linked by a disulfide bond The Basics of Thiols and

(PubMed) Harrison J, Rentz DM, McLaughlin T, et al

doi: 10.1038/s41589-021-00767-w 131 ZuccarelliR.Rodrguez-RuizM.Lopes-OliveiraP

This review systematically summarizes the molecular mechanisms underlying the dynamic equilibrium of cellular redox state, including the intracellular sources of ROS and the multilayered antioxidant defense network

Acknowledgements This work was supported by the Swedish Brain Foundation (grant FO2023-0241), the Swedish Research Council (VR-NT grant 2022-04198, VR-TVAR 2021-03293), and the Science for Life Laboratory (all to P.E

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