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The resulting cells displayed oxidative imbalance, reduced cellular and mitochondrial respiration rates, lower ATPase transcript levels, decreased mitochondrial membrane potential, and impaired mitochondrial complex activity

Theres no recommended upper limit for B12, so overdosing is not a concern

[DOI] [PubMed] [Google Scholar] 92.Gupta S., Sharma T.K., Kaushik G.G., Shekhawat V.P

The damage caused by free radicals is often inevitable and typically managed by cellular repair mechanisms

10.1016/j.cbpa.2010.09.013
