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(4) Key Enzymes and Co-Factors: The figure highlights important enzymes such as methionine synthase ( MS ), cystathionine beta-synthase ( CBS ), and dihydrofolate reductase ( DHFR ), and essential co-factors like vitamin B12 and folate (B9) derivatives

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OECD Guideline for testing of chemicals

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doi: 10.3390/ijms22126532

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