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Chronic hypoxemia, commonly seen in the advanced stage of COPD, stabilizes the HIF-1, which promotes microglial activation, oxidative stress, and cellular injury within the CNS [24]

Symptoms and treatment burden associated with cancer treatment: Results from a cross-sectional national survey in the U.S

Int J Oncol (2018) 53:21524

M., Hastings, R
Reversely, microbiota-host interactions also contribute to disease susceptibility and progression
