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Abnormal activation or inhibition of the Wnt signaling pathway has been observed in different cell types within the nervous system, including neurons, microglia, astrocytes, oligodendrocytes, and ECs

doi: 10.3389/fonc.2025.1701249 Received 08 September 2025 Revised 13 November 2025 Accepted 20 November 2025 Published 03 December 2025 Volume 15 - 2025 Edited by Ashish Tyagi, Texas A and M University, United States Reviewed by Matteo Borgini, Wellstar-Medical College of Georgia Health, United States Xiangfei Xue, Shanghai Jiao Tong University, China Updates Copyright 2025 Tunc, Ates, Ylmaz, Medoro, Davinelli, Suzen and Saso

Expression of an active glycosylated human gamma-glutamyl transpeptidase mutant that lacks a membrane anchor domain