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There was a general concentration-response trend identified across all groups, with higher concentrations of erinacines and HEME eliciting a stronger cellular response
According to the research conducted by Fabian et al

Hostettler, L., Grundy, L., Kser-Pbernard, S., Wicky, C., Schafer, W

Choi SW, Gu Y, Peters RS, Salgame P, Ellner JJ, Timmins GS, Deretic V

MSH forms conjugates with xenobiotics and antibiotics either spontaneously or by the DinB-family MSH S -transferases (Newton et al., 2011)
