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ATF3 can activate transcription and expression of RNF146, thereby inhibiting OGD/R-induced neuronal ferroptosis
Furthermore, in animal experiments, it was observed that elevated neutrophil infiltration into muscle, kidney, and liver may exacerbate tissue injury (149, 150), and neutrophil depletion can be a factor alleviating liver damage following exhaustive exercise (150)

Mechanisms and efficacy of heat and cold therapies for musculoskeletal injury

Moreover, D-galactose-induced aging model found that methionine intake improved cognitive function, reduced oxidative stress and inflammation, and upregulated the TSP
