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Consequently, loss of FMRP results in an aberrantly increased mGluRI expression in these neurons, leading to enhanced mGluR-related long-term depression causing cognitive impairments and intellectual disability

Notes Shaik Nyamathulla and Syed Mahmood (Department of Pharmaceutical Technology, Faculty of Pharmacy, Universiti Malaya, 50603 Kuala Lumpur, Malaysia

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It has historically been criticized because digestive enzymes can break down glutathione before it reaches circulation intact
The increased frequencies indicate that dendritic spines induced by Nle'- AnglV or dihexa support functional synaptic transmission
