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Finally, a pilot study realized on 12 CF volunteers supported that nebulized NaHCO 3 was safe and well tolerated and it permit to increase ASL pH and change the rheology of the sputum (Gomez et al., 2020)

High-throughput screening platforms, computational drug discovery approaches, and structure-activity relationship studies should be employed to optimize the specificity and potency of these agents

Please note that the range of symptoms experienced and the causes of peripheral neuropathy we have discussed above is not exhaustive

2015;10:e0128347

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