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The bioregulator slowed down aging of the reproductive function, decreased physical activity, inhibited free radical processes, and decreased total spontaneous tumor incidence 1.7 times in female CBA mice.54 Epitalon inhibited mammary carcinogenesis and metastasis in HER-2/neu transgenic mice.55 The expression of HER-2/neu mRNA in the mammary tumors of HER-2/neu transgenic mice treated with Epitalon reduced 3.7-fold in comparison with the control animals