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Oxidative stress can arise from various factors, such as air pollution, cigarette smoking, alcohol consumption, or even emotional stress

Materials and methods Ethic statements The animal studies were carried out in strict accordance with the Detailed Rules for the Administration of Animal Experiments for Medical Research Purposes issued by the Ministry of Health of the Peoples Republic of China and were approved by the Animal Experiment Administration Committee of The Fourth Military Medical University

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The Rome medical establishment serves a regional population estimated at more than 500,000 in two states