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Amide I and II bands (1,650 cm and 1,550 cm) shift upon copper binding, indicating interaction with peptide carbonyl and amine groups

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Swann, R., Laskowski, D., McCall, P., Vander Kuy, K

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Its use is limited by a broad side-effect profile, including anticholinergic effects (e.g., dry mouth, urinary retention), sedation, and orthostatic hypotension

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PMID 16537422

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The single research hypothesis available to laboratories using the Klow blend is whether each component produces the same endpoint changes when prepared under matched conditions, versus when prepared and assayed in isolation

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