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Rutin isolated from Lonicera japonica showed a protective effect towards myocardial damage mediated by H 2 O 2 -induced oxidative stress in both H9c2 cells in vitro and rat myocardial ischemiareperfusion injury model in vivo
The extracellular matrix (ECM) is a network of extracellular macromolecules, enzymes, collagen, and other biomolecules that provide support for surrounding cells

Furthermore, cellular experiments in a high-altitude rat model have shown that butyrate can downregulate the expression of HIF-1 by reducing the activity of lactate dehydrogenase A, which in turn attenuates the glycolytic pathway and alleviates cellular responses to hypoxic stress (Zhao et al., 2024)

99mTc-depreotide tumour uptake in patients with non-Hodgkins lymphoma
doi:10.1016/j.freeradbiomed.2013.08.163