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The second step is catalysed by GSS and involves the condensation of -glutamyl cysteine and glycine to form GSH

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478 Another randomized clinical trial showed that postoperative curcumin (500 mg) effectively reduced pain and fatigue in patients who underwent laparoscopic cholecystectomy

In addition, it has been demonstrated that ROS are also actively involved in the formation of NETs [109], autophagy [110,111,112], chemoattraction and activation of the inflammasome [113,114,115], programmed cell death of infected reservoirs [116, 117], antigen presentation, T-helper cell activation and lymphocyte proliferation [118,119,120,121]