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muciniphila and Lactobacillus , and reduces the abundance of harmful proinflammatory bacteria, such as Desulfovibrio , Turicibacter , and the Lachnobacterium genus of the Firmicutes phylum [37,205,215,219] (Figure 5B)

In the long-term extension to 52 weeks, those continuing treatment maintained VAT reductions of approximately -18%

This makes milk thistle especially useful during recovery from liver inflammation or mild liver damage

In addition, patient stratification is taking further shape with active research groups developing more reliable epigenetic mapping and multiplex biomarker panel approaches to substantiate biological endophenotypes such as BDNF hypermethylation that serve as biological hieroglyphics for cognitive decline or mood disorders

This integration of organoids with in vivo bioelectronics could contribute to a more intuitive and systematic mode of communication with the brain in the future