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To test this, scientists used an exercise-challenge model in both rodents and humans to induce inflammation and evaluate whether the ability of L-carnitine tartrate to downregulate ACE2 expression could translate to an attenuation of SARS-CoV-2 infectivity in an in vitro human lung epithelial cell-based system 5

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TMAO and HF HF is defined as a group of syndromes caused by structural or functional damage that results in impaired ventricular filling or cardiac output, and which involves multi-organ and systemic neurohumoral dysfunction (89)