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Therefore, mitochondrial enhancers such as NAC might be best, not as treatments of acute mood episodes, but as add-on maintenance therapies to manage difficult-to-treat subsyndromal symptomsan area of great clinical need

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Journal of the International Society of Sports Nutrition, 18 , 1

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The DCCT found that modifying treatment regimens to achieve tighter glycemic control led to a dramatic 60% reduction in diabetic neuropathy after five years (Genuth 2006)