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362 The administration of calcitonin successfully reduced the levels of urinary deoxypyridinoline in GLP-1R knockout mice
Assays like qPCR can be useful, but they are sensitive to technical and biological variability

The mice were pretreated with dopamine antagonist haloperidol (5.0 mg/kg i.p.) and subsequently treated with amphetamine (20 mg/kg i.p.1, 2, 4 and 10 days after haloperidol pre-treatment), which is usually used for the study of behavioral supersensitivity to an amphetamine stimulating effect

Patients inject 5 days on, 2 days off, every month, on a 3-month active cycle followed by a 2-month rest period before repeating
