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1979 Jun;139(6):717-9

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Surgical trauma selectively reduced GS activity, which probably became rate-limiting (Luo, et al., 1998)

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SIRT1 is also known as the longevity gene because of its role in reducing the risk of diabetes, obesity, metabolic syndrome, atherosclerosis and other forms of cardiovascular disease, kidney disease, liver disease, neurodegeneration, and cancer