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Description
Thiamine deficiency leads to an accumulation of metabolic intermediates, such as pyruvate and lactate, which stabilize HIF-1 through inhibition of prolyl hydroxylases (PHDs), thereby inducing HIF-1-mediated gene expression (49)

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doi: 10.1080/10408398.2022.2092054 219 Rajaei EHHMowlaKZayeriZD

(NOx) 391.8 282.7 M (T0) vs

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