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Furthermore, ETBF can induce Th17 cell differentiation via METTL14-dependent m 6 A methylation, downregulating tumor-derived exosomal miR-149-3p, thereby promoting CRC cell proliferation [78]

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The broader preclinical record, reviewed exhaustively by Graf and Kastin [4, 5], includes sleep-architecture effects in rats and mice, and predominantly REM-related effects in cats a species-specificity that the delta sleep-inducing name does not capture