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10.1016/j.regpep.2009.05.008 [DOI] [PubMed] [Google Scholar] 20
The peptide reaches peak plasma concentration while endogenous nicotinamide levels are at their circadian low point, which occurs in the early morning hours before food intake
Yuan Z., Li J., Zou X., Liu C., Lu J., Ni C., Tang L., Wu X., Yan F., J
Wang W, Wang X, Luo J, Chen X, Ma K, He H, et al
This may lead to insulin resistance, weight gain, obesity, and type 2 diabetes
