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[19] The overall net reaction, using palmitate (16:0) as a model substrate is: 8 Acetyl-coA + 7 ATP + 14 NADPH + 6H+ palmitate + 14 NADP+ + 6H2O + 7ADP + 7P Cholesterol biosynthesis [edit] Cholesterol can be made from acetyl-CoA through a multiple-step pathway known as isoprenoid pathway
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