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CPT1A has a higher affinity for its substrate carnitine and a lower affinity for the physiological inhibitor malonyl-CoA than does the muscle isoform
Fan & Simmen, 2019
The health benefits of omega-3 polyunsaturated fatty acids: A review of the evidence
Clin Cancer Res 23(15):4146-4154, 2017
FIN56 promotes ferroptosis via the inhibition of autophagy-dependent protein degradation of GPX4, acting as a type 3 FIN, which represent a distinct class of ferroptosis-inducing agents that promote cell death by selectively inhibiting autophagy-dependent degradation of GPX4, rather than directly targeting GPX4 activity or GSH) synthesis (111)
