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elegans , in agreement with the toxicity of this strain observed in previous screens 46

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Compounds such as grape seed proanthocyanidins (GSPs) have demonstrated protective effects against DPN by alleviating endoplasmic reticulum stress and enhancing antioxidant defenses

In addition, some agglomeration of the nanoparticles in aqueous solutions is expected due to the magnetism of magnetite NPs [49]