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Description
The first one involves irreversible damage to the ETC, possibly through TTC5 upregulation, resulting in ATP loss, increased mitochondrial superoxide production and caspases 3/7 activation, and subsequent apoptosis

Under this scenario, the measure's baseline year will remain CY 2022/2023, but the measure's first performance year will be CY 2025/2026

Note: Model 1: crude Model 2: according to age Model 3: correlated with age, smoking status, body mass index, hypertension, and diabetes mellitus Table 2

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