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Although GSH is not alone responsible for these protective mechanisms, the hepatic production of GSH seems to be essential to survival, with knockout mice dying within months secondary to inflammation and hepatic steatosis resulting in liver failure [21]
[DOI] [PubMed] [Google Scholar] Carro E, Trejo JL, Gerber A, Loetscher H, Torrado J, Metzger F, Torres-Aleman I
Physiological Aspects of ROS in Aging System-wide, ROS affect organs differently
Franklyn, K
Pfeffer et al
