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Furthermore, FAO capacity, measured by palmitate-stimulated OCR and expression of FAO enzymes (CPT1a, ACADL), is significantly impaired, preventing the metabolic reprogramming required for M2 activation (Liu et al., 2023)

Additionally, VEGF-B (isorform B) was found activated in a rat brain model following treatment with 40 nM rotenone, and showed neuroprotective actions by improving neuronal survival (Falk et al., 2009)

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