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If you are sensitive, or you experience fatigue as opposed to an increase in energy when taking vitamin B12 then using a smaller dose less frequently will likely be better for your body

Kaupmann et al., 1998

Factors like diet, stress, and nutrient absorption all influence B12 levels

Regardless of their differences, all of these disorders are associated with intellectual disability, motor abnormalities, and behavioral abnormalities

They increase dopamine, acetylcholine, serotonin, or GABA to produce short-term improvements in focus, mood, or alertness
