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(2025) demonstrated in an intracerebral hemorrhage (ICH) model in mice that HO-1 activates microglia in the later stages of ICH, promotes phagocytosis, enhances the absorption of hematomas and cellular debris, induces neurogenesis and angiogenesis, and thus facilitates brain tissue recovery while attenuating secondary brain injury

[DOI] [PubMed] [Google Scholar] 5.Caputo T, Gilardi F, Desvergne B