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By binding to two different epitopes of CD38, these constructs facilitate the formation of C1q-activating oligomers, thereby increasing the interaction with C1q and enhancing the CDC effect [93]

Headaches or tiredness are occasionally reported because of alterations in metabolism and appetite control

A recent study conducted on mice models of PD established that the N-homocysteinylation of -SN enhances its aggregation potential and increases its neurotoxicity and that higher Hcy levels correlated with more severe -synuclein deposition within mouse brains (Zhou et al

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