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It also plays a critical role in the body's immune response and anti-viral defenses

Indeed, when 2-DG and metformin simultaneously target glycolysis and mitochondrial complex I, T cell metabolism is normalized and lupus disease is reduced in mice, thus highlighting the importance of both glycolysis and mitochondrial metabolism in T cell function and autoimmune diseases (74, 76)

Importance of SAMe in Cellular Processes Considering the wide variety of biochemical reactions in which it participates (Figure 1), as well as the numerous pathways with which it interacts, it is easy to understand the importance of SAMe for fundamental cellular processes

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Insufficient daily selenium intake can lead to selenium deficiency, while excessive daily selenium intake can lead to selenium poisoning [12]