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Ding C, Ding X, Zheng J, Wang B, Li Y, Xiang H, et al

Shaking creates mechanical stress and shearing forces that can break the fragile peptide bonds, rendering it useless

Designing drugs optimized for both bloodbrain barrier permeation and intra-cerebral partition

In certain cancer cells, TMEM164 is needed for the formation of the ATG12ATG5-ATG16L1 complex and subsequent degradation of GPX4 induced by ferroptosis activators (such as erastin or RSL3) (Figure 6) [76]

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