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More importantly, the major finding in our study was the prompt recovery or dynamic reversion to similar pre-treatment baseline levels of gut microbiota and resistome one week after amoxicillin-clavulanic acid cessation for both probiotic and placebo groups (with the exception of minor taxon differences)

The selective targeted drug delivery to the site of action within the body without affecting healthy organs and tissues results in improved efficacy and lower side effects (137)

Leann Silhan, MD Reference: Colpo E

For example, GPR40-deficient mice with a low-fat diet (LFD) show metabolic abnormalities, including an increase in body weight, insulin resistance, and levels of cholesterol and ALT [196]

Our study revealed that GHK-Cu treated 5xFAD mice exhibited superior cognitive performance compared to saline-treated cohorts while also demonstrating a reduction in amyloid plaques in the frontal cortex and hippocampus