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Digestive or malabsorption issues (e.g., gastrointestinal diseases) leading to B12 deficiency

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Structure and functions of the immune system The human immune system consists of many organs functionally connected

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In 2010, TYSABRI clinical trial data were used to define a new outcome: freedom from disease activity, 15 defined as absence of EDSS progression, relapse, or new/newly enlarging MS lesions

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These are generally transient and resolve with dose titration or as the body adapts

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