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Phase II enzymes such as GSTP1 and GSTA1, found in several mammalian species and non-tumorous liver tissues [14] are the first step in the mercapturic acid pathway, which leads to the excretion of the xenobiotics

Annu Rev Environ Resour 35:5775
It appears that the absence of mitochondria in this case is not an ancestral characteristic, but instead a secondary loss incident

The mechanism is attributed to the drug class
