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however, even these lesions persisted for an average of 7.8 years


This discovery, reported in Cell Metabolism , challenged the traditional view of mitochondria solely as power generators and introduced the concept of bidirectional mitochondrial-nuclear communication

Moreover, diisopropylamine dichloroacetate (DADA), an inhibitor of PDK, enhanced radiosensitization in esophageal squamous cell carcinoma by increasing mitochondria-derived ROS levels [56]

doi: 10.1016/j.expneurol.2012.08.023
