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It is generally well-tolerated and backed by scientific reasoning related to brain health

These included reductions in functional and cardiovascular age, greater exercise tolerance, and notably lower mortality: treated individuals had 28% fewer deaths overall, about half the cardiovascular mortality, and reduced incidence of heart failure & respiratory disease compared to controls

Some studies show that anywhere between 200-800mcg per day is safe

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The research reported herein received funding from the European Research Council under Grant Agreement 323646 for a project entitled Chemical Youth ( In the review and decision process, the editor of AE , Niko Besnier, was seconded by Associate Editor Paige West because of his conflict of interest with the first author