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2 Mechanisms of oxidized lipid generation 2.1 Stent implantation-induced oxidative stress The implantation of carotid stents initiates a cascade of oxidative stress responses that fundamentally alter the local vascular microenvironment (Figure 1)

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Perer et al 31 confirmed the upregulation of stress-responsive genes ( HMOX1, HSPA6, CRYAB, XRCC2 ) and advanced glycation end products (AGEs) following DHA exposure

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