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Apple Polysaccharide inhibits microbial dysbiosis and chronic inflammation and modulates gut permeability in HFD-fed rats

The potential of TMAO to result in atherogenic effects is linked to alterations in cholesterol and bile acid metabolism, inflammatory pathway activation, and foam cell formation promotion
High glucose induces mitochondrial morphology and metabolic changes in retinal pericytes

SOAR and the polybasic STIM1 domains gate and regulate Orai channels