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Several studies conducted with higher doses of sulforaphane in mice do describe toxicities that require careful attention to risk-benefit analyses and determination of therapeutic or prophylactic indices

Hyperhomocysteinemic subjects also had raised serum levels of MMP-9 comparing healthy controls, and although IL-10 markedly suppressed MMP-9 release from PBMCs in controls, no or only minor effect was seen in hyperhomocysteinemic subjects [91]

Any excess or unwanted vitamin B-12 is excreted in the urine

Vitamin C deficiency and its association with psychiatric effects have been known for many years

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