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Jastreboff AM, Kushner RF

Under homeostatic conditions, Nrf2 is bound to the Keap1 protein in the cytoplasm and undergoes continuous ubiquitination and proteasol degradation [73, 74]

Am J Physiol Endocrinol Metab 292:E353E358

Yang SC, Atluri P, Boden NJ, Donington JS, Ikonomidis JS, Lagisetty KH, Rice DC , Sengewald DE, Tseng EE, Weyant MJ, Savage Yohe C

Medication from a rectal suppository tends to work quickly