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This study aims to deepen our understanding of the gut-brain interactions in the treatment of depression, hoping to provide a theoretical basis and experimental support for novel antidepressant treatment strategies based on microbiome modulation

Numerous data are indicative of the decreased concentration of reduced glutathione and increased concentration of oxidized glutathione in plasma [47, 48], erythrocytes [49], cerebrospinal fluid [50], and different brain regions [5052] in first-episode, nonmedicated, medicated, and chronic schizophrenia patients

Increased O-GlcNAcylation of SNAP29 drives arsenic-induced autophagic dysfunction

The Firmicutes and Bacteroidetes (F/B) ratio is important to maintain intestinal homeostasis

doi: 10.1111/jfbc.13612 111 NakagawaY