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This process is not accompanied by the generation of ROS, rather, XO uses molecular oxygen, which is delivered during reperfusion as an electron acceptor to produce superoxide radical anion
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[4] DORR R T, LINES R, LEVINE N, et al
Further, chronic injections of METH activate programs that prevent DA toxicity without influencing drug-induced pathologic changes in serotoninergic systems (Shen et al., 2016
