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Description
Chaperones attempt to remedy the unfolded protein first and, if unsuccessful, activate cellular programs, including the UPR, heat shock response (HSR), and ER-associated degradation (ERAD), to induce processes to either fix the problem or destroy the unfolded proteins (324, 325)

Leise MD, Poterucha JJ, Kamath PS, Kim WR (2014) Management of hepatic encephalopathy in the hospital

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doi: 10.1080/00498250701802514

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