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However, experiments in humans have shown that an experimental low-zinc diet can lead to a number of biochemical abnormalities, including decreased serum testosterone level, decreased natural killer cell activity, decreased activity of serum thymulin (a zinc-dependent hormone produced by the thymus and important for immune function), hyperammonaemia, decreased taste, decreased visual dark adaptation and decreased lean body mass

Int J Gynecol Cancer (2023) 33(3):3517

Heterogeneity of dog-liver glutathione S-transferases

However, increasing GH and insulin-like growth factor-1 in cancer patients raises concerns of potentially stimulating tumor growth

Vitamins B6, B12, and E also support glutathione production and function.