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In addition to L-carnitine contribution to spermatogenesis, it can protect germ cells as an antiapoptotic factor by interfering with extrinsic Fas-FAS-Lmediated pathway (through intervening with Fas-triggered apoptotic signals and preventing ceramide generation) and intrinsic mitochondrial-dependent pathway (by inactivating caspases 3, 7, and 8) that are common effectors of apoptosis

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Theodore J Gaeta