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Description
A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Abeta
Here's the mechanism: the enzyme ALDH2 (aldehyde dehydrogenase 2) oxidises acetaldehyde into acetic acid, but this process requires adequate glutathione reserves to neutralise reactive oxygen species (ROS) generated during the reaction
doi: 10.3390/vaccines9080911
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Moreover, studies have shown that CTR1-dependent Cu import activates the mitogen-activated protein kinase (MAPK) signaling cascade
